Lab Services Overview

At Synaptigen, our lab services combine scientific precision with agile, patient-focused development. We offer comprehensive support across early discovery, preclinical, and translational phases to accelerate your path from bench to clinic.

Bioanalytical

We provide high-sensitivity quantification of drugs, metabolites, and biomarkers in biological matrices using validated LC-MS/MS and other platforms. From method development through regulatory-compliant sample analysis, our team ensures data integrity across all study phases.

ADME

Our ADME (Absorption, Distribution, Metabolism, and Excretion) services generate decision-enabling data to optimize compound selection and design. We assess in vitro and in vivo metabolic stability, plasma protein binding, permeability, and clearance to inform dosing and safety strategies.

CMC (Chemistry, Manufacturing, and Controls)

Our CMC team partners with you to ensure seamless scale-up from discovery to clinical trial material. We support formulation development, stability testing, analytical method validation, and regulatory documentation aligned with FDA and EMA expectations.

Genomics

Leverage targeted and whole-genome solutions to discover biomarkers, understand disease pathways, and guide personalized treatment strategies. Our genomics capabilities support patient stratification, pharmacogenomics, and companion diagnostic development.

In Vivo Pharmacokinetics

We design and execute robust PK studies in rodent and non-rodent species, utilizing non-compartmental and population PK modeling to characterize drug behavior. Our team delivers rapid turnaround on bioavailability, half-life, clearance, and tissue distribution data to guide clinical readiness.

First-in-Rodent Studies

Our First-in-Rat® and First-in-Mouse® platforms provide early non-GLP safety and PK insights. These studies are tailored to identify go/no-go signals efficiently, enabling strategic decisions for IND-enabling toxicology packages.

Single Dose / Repeat Dose Studies

We offer flexible study designs for acute and subchronic dosing, assessing exposure, safety margins, and target organ toxicity. Each study includes expert pathology review, TK/PK analysis, and actionable recommendations.

In Vivo Drug Metabolism

Our in vivo metabolism services profile parent compound and metabolite kinetics to uncover species-specific metabolic pathways. We integrate mass balance studies, metabolite ID, and bioactivation risk assessments to support IND submissions.

Medicinal Chemistry

From hit-to-lead to candidate nomination, our medicinal chemistry services focus on structure-activity relationships, synthetic optimization, and compound profiling. We emphasize strategies that enhance potency, safety, and developability.

Screening Support

We offer fast, reliable hit identification using customized biochemical and cell-based assays. Our approach accelerates early-stage discovery with actionable data.

Our Core Services

Connections That Matter

• We connect biotech, pharma, and CROs with the right partners to fill critical gaps and drive therapies from discovery to approval.

Nonclinical & Early Development Services

• Optimize early drug development with First-in-Rodent® studies, in vitro ADME, and model-informed PK/PD. We support candidate selection, dose prediction, and Pre-IND readiness.

Strategic Lead Generation

• Our precision-driven outreach builds a pipeline of high-quality leads tailored to your research and business goals.

Content Development & Engagement

• Through compelling, industry-focused content, we elevate brands, simplify complex ideas, and drive engagement for biotech, pharma, and CROs.

Patient Integration Solutions

• We embed the patient voice into every phase of drug development, improving clinical trial success and ensuring better-informed strategies.

Augmented & On-Demand Consulting Programs

• We provide expert drug development support, when you need it. Access specialized expertise without the overhead of full-time employees. Our flexible consulting programs provide high-impact Drug Development and clinical trial services on your terms - pay only for what you use, scale up or down as needed, and leverage our expert teams to accelerate your projects.